Sunday sees the first Wear-Tyne derby after 2024, but who will emerge victorious – the Black Cats or Newcastle?
"For most of last season, you couldn't have imagined the Wearside club earning promotion and holding their own with Eddie Howe's Newcastle, never mind being above them in the table," commented analyst Chris Sutton.
"The situation is very different now, and the way they play makes me think they've got a genuine opportunity."
The analyst is providing scoreline guesses for all 380 Premier League games this season, against artificial intelligence, fans and a variety of guests.
For week 16, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the England's esports team – the Football Association's recognised esports team – at the EA Sports FC European esports championship finals tournament, which is being held at Twickenham Stadium on Saturday.
Viewers can catch Uefa's video platform, IG Live and short-form video channels, as well as the official Twitch channel and its YouTube counterpart and the national team's Twitch.
Do you agree with their forecasts? Share your own projections below.
The most popular scoreline picked for each game is featured in the tables at the bottom of this page.
Predicting the right outcome (picking a win, draw or defeat) is worth 10 points. An accurate scoreline earns 40 points.
Ray, who also plays Gen City and Manchester City as well as England, is entering the fray at the eEuros finals after successfully navigating the preliminary stage.
The final eight competitors will represent their nations at the finals in a straight knockout, playing for a six-figure prize fund and a coveted spot in the world finals play-offs, with Denmark's Anders Vejrgang looking to retain the title he won last year.
"I am feeling really good for it," Ray remarked. "I've got a really good coach by my side and practice has been going well.
"Representing your country is always an honour to play for your country. Obviously when you are younger, you imagine doing it as an real-life footballer, but when you pursue a career in this profession and there is an chance to represent England, putting the shirt on is something unique.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him throughout the year just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"I believe he is the number one in the world so getting a win over him in a tournament like this just delivers a crazy boost of confidence."
Stamford Bridge, 15:00 GMT
The London club were impressive against Arsenal at the end of November, when they secured a point after being reduced to 10 men, and many thought this is it, they could possibly be challengers for the crown.
Since then, however, they were beaten physically by Leeds, looked lethargic against Bournemouth and this week got defeated by Atalanta in the Champions League.
So head coach Enzo Maresca really needs a win here to restore momentum, but it won't be easy because the Toffees are such a dangerous team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing really well and they have got a bit of momentum at the moment.
Current evidence suggests you would likely back the visitors, while the most prudent prediction would probably be a draw, but I'm throwing caution to the wind.
They have not given me any real reason to back them recently, but I just have a gut instinct they will emerge victorious because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Anfield, 15:00 GMT
I am at this game and it will be intriguing to see what we get from Liverpool.
It was great to see for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot shouldn't need to put up with that distraction. I know Salah has been a icon for Liverpool but fundamentally Slot just wants to win games and there is no ulterior motive in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond formation and two up top.
Everyone is going to be talking about whether Salah is included for this game, but the only way he is going to be reintegrated is if he says sorry.
Slot's primary concern will be on winning this game, but it is a difficult fixture.
It's fair to say it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to stringing wins together, but I am not sure how much their exertions at the San Siro will have drained them.
I have whacked a couple of Brighton players in my Fantasy Premier League side, so they will almost certainly blank - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Stadium of Light, 14:00 GMT
The Wearside club have had the week off while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to let their lead slip away late on.
Aside from their excellent performance against Everton a couple of weeks ago, Newcastle's away form has been poor, particularly straight after they've played in the Champions League.
The pattern suggests that tendency to continue on Sunday, and their lack of freshness is likely to be a significant issue in how this game goes because of their rivals' intensity.
We saw how incessant Regis le Bris's side are. They dominated the Gunners, and it was amazing to watch.
Many pundits talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been excellent, but Noah Sadiki, who plays in midfield with him, has also been one of the top transfers and warrants praise too.
I am expecting this being the best game|most exciting fixture
A tech journalist and digital strategist with over a decade of experience covering AI, cybersecurity, and startup ecosystems across Europe.